Retatrutide
Retatrutide (LY3437943) is a triple agonist, acting at the GIP, GLP-1 and glucagon receptors from a single molecule.
Volume discounts up to 35% off — buy more, save more.
Orders of three or more vials include a 5 ml vial of bacteriostatic water, complimentary. Also available separately, $10.
Volume Pricing — tap a tier to set quantity
Research use only. Not for human or veterinary use. Not FDA approved. Supplied as lyophilized powder in a sterile vial for in-vitro laboratory research by qualified professionals.
Certificate of Analysis — Batch Documentation
Batch history
Each lot is independently analyzed before release. The figures above are taken directly from the lab report for the batch currently shipping; the report itself is available on request.
Storage & Stability — Research Handling Guidance
- 🧊Lyophilized (sealed vial): store at −20 °C; typically stable 24+ months.
- ❄️Reconstituted: refrigerate at 2–8 °C and use within ~30 days.
- 🔄Avoid repeated freeze/thaw cycles — aliquot before freezing if needed.
- 🌞Protect from light — keep the vial in its carton or amber storage.
General peptide storage guidance for laboratory settings. Research use only — not for human or veterinary use.
About Retatrutide
Retatrutide, designated LY3437943, was engineered to act at three energy-balance targets simultaneously: the GIP receptor, the GLP-1 receptor and the glucagon receptor. Adding the glucagon arm to the two incretin receptors is what separates it from the single- and dual-agonist peptides that preceded it, and it is the reason the compound attracts the volume of preclinical and clinical attention that it does.
Research using retatrutide concerns glucose handling, energy expenditure, lipid metabolism and body-composition models. It is supplied as a lyophilized powder for reconstitution in a suitable solvent under laboratory conditions, at ≥98% purity, with the Certificate of Analysis for the current lot available on request. Sold for laboratory research use only; not for human or veterinary use.
What Is Retatrutide (LY3437943)?
Retatrutide (INN: LY3437943, CAS: 2381089-83-2) is an investigational triple incretin receptor agonist developed by Eli Lilly. It is the first peptide in its class to simultaneously target three receptors: the GIP receptor (glucose-dependent insulinotropic polypeptide), the GLP-1 receptor (glucagon-like peptide-1), and the glucagon receptor.
This triple-receptor mechanism distinguishes Retatrutide from earlier-generation compounds. Semaglutide activates only GLP-1 receptors; tirzepatide activates both GLP-1 and GIP receptors. Retatrutide's additional glucagon receptor agonism adds a third dimension to its metabolic research profile, making it the subject of active Phase 3 clinical investigation.
Our Retatrutide is supplied as lyophilized powder in a sterile vial, tested at ≥98% purity by HPLC with mass spectrometry identity confirmation. A Certificate of Analysis (CoA) is available for every batch. For in-vitro research and laboratory use only. Not for human consumption.
Retatrutide — Frequently Asked Questions
What is Retatrutide?
Retatrutide (LY3437943) is a triple agonist, acting at the GIP, GLP-1 and glucagon receptors from a single molecule. It is identified by CAS number 2381089-83-2, a molecular weight of ~4731.3 g/mol.
What purity is Retatrutide supplied at, and can the analysis be seen?
The lot currently in stock was assayed at 99.2% by HPLC. The Certificate of Analysis recording that figure is available on request.
In what form does Retatrutide arrive, and how should it be kept?
Retatrutide arrives as a lyophilized powder in a sterile vial. Keep the powder cold and out of the light. Once it has been reconstituted for research, refrigerate it and handle it according to standard peptide-stability practice.
Which quantities of Retatrutide are stocked, and what do they cost?
Retatrutide is stocked in 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg. Pricing begins at $90.00 per vial and falls on larger quantities, by up to 35%. US shipping is free on every order.
Can Retatrutide be used in humans?
No. Retatrutide is supplied strictly for in-vitro laboratory research by qualified professionals. It is not for human or veterinary use, and it is not approved by the FDA for any therapeutic purpose.
How is an order for Retatrutide placed and paid for?
Add Retatrutide to the cart and check out on the site. Payment is by PayPal or Bitcoin. Orders placed before 2 PM ET are dispatched from the US the same day payment clears; later orders go out the next day. If Bitcoin is unfamiliar, a short guide is linked at checkout.
Related products
More in GLP-1 Receptor Agonists.
